ATP Vitality Coenzym Q10 Maximal 90 tob

Coenzyme Q10 200 mg - support cellular energy and antioxidant protection

Coenzyme Q10 is an important endogenous substance present in the mitochondria of cells, where it participates in the formation of adenosine triphosphate (ATP) and also acts as an antioxidant.

Capsules with 200 mg of CoQ10 offer a higher dose, which in many clinical studies appears to be effective in supporting certain parameters - oxidative stress, glycemia, metabolic processes.

Mechanisms of action

• 1. Energy metabolism: CoQ10 is part of the respiratory chain in mitochondria - it transfers electrons between complexes I/II and III, thus contributing to ATP synthesis.
• 2. Antioxidant effect: Acts as a lipid-soluble antioxidant, helps regenerate vitamin E, helps protect cell membranes and mitochondria from lipid peroxidation.
• 3. Glycemic control: A relatively new meta-analysis has shown that doses in the range of 100-200 mg/day have a significant effect on lowering glycemia. See below

Why choose the 200 mg dose

• The literature and studies show that for many parameters the "optimal" dose is 200 mg/day.
• Absorption studies show that 200 mg is the threshold point at which a significant rise in serum CoQ10 levels is achieved.
• 200 mg is a "significant premium dose" with the support of clinical data for the target group seeking superior supplementation.

Benefits

• Middle-aged and older individuals experiencing a reduction in endogenous CoQ10 production (e.g., age 40 and older). As age increases, its production decreases, and it is therefore advisable to supplement coenzyme Q10 in the diet. Its lower levels may also be affected by taking cholesterol-lowering drugs (statins).
• Athletes or active people - there are studies that 200 mg of CoQ10 can improve BV (bioavailability), reducing oxidative stress during exercise.

Recommendations for users

• The recommended dose is 200 mg per day - do not take a higher dose.
• For people taking anticoagulants, hypotension, antidiabetic drugs, or if pregnant or breastfeeding, it is recommended to consult a physician before taking.
• The supplement should always be taken with a fat-containing meal for better absorption.

A dietary supplement containing 200 mg of coenzyme Q10 is a well-studied choice for users seeking cellular energy support and antioxidant protection.

Study

Effects of coenzyme Q10 supplementation on glycemic control: A GRADE assessed systematic review and dose response meta analysis of randomized controlled trials (2022)

40 RCTs with a total of 2,424 participants were analyzed.

Results: CoQ10 supplementation significantly reduced:

• fasting glucose (WMD: -5.22 mg/dl; 95% CI: -8.33, -2.11)
• fasting insulin (-1.32 µIU/ml; 95% CI: -2.06, -0.58)

(-0.12%; 95% CI: -0.23, -0.01)
• HOMA-IR (-0.69; 95% CI: -1.00, -0.38)

And very relevant to your question: in a dose-response analysis, it was found that 100-200 mg/day had the greatest effect for reducing glucose, insulin, HbA1c and HOMA-IR.

For example, the authors state, "A 'U' shape dose-response relationship

curve

revealed that 100-200 mg/day of CoQ10 largely decreased fasting glucose .

Dosage recommendation:

• Take 1 capsule daily with plenty of water.